Heartworm & Intestinal Parasites · dogs

Heartgard Plus price comparison

Heartgard Plus is a monthly prescription chew that prevents heartworm disease and treats roundworms and hookworms in dogs. It is one of the few big-name preventatives with true generic competition, which makes comparing prices especially worthwhile.

Comparing: 6-pack (6 monthly chews), 26–50 lb Prices last verified Jul 18, 2026
Pharmacy Price per dose Last checked Link
1-800-PetMeds Lowest per dose $75.49 $12.58 Jul 18, 2026 Check price →
Allivet $75.49 $12.58 Jul 18, 2026 Check price →
PetCareRx List price $83.69; extra discount in cart with code CARE25 $75.50 $12.58 Jul 18, 2026 Check price →
Chewy Check site First check pending Check price →
Costco Pharmacy Membership required. No affiliate program exists, and we include it anyway: proof that rankings are not pay to play. Check site First check pending In warehouse / member site
Petco Check site First check pending Check price →
Walmart Pet Rx Check site First check pending Check price →

Ranked by verified per dose only; ties listed alphabetically. Unverified pharmacies are listed alphabetically below priced ones. Outbound links may become affiliate links; that never affects the order. Disclosure · Methodology

Price history: tracking since Jul 18, 2026. Trend charts appear once we have multiple verified checks on record.

Get an email when this price drops

We recheck Heartgard Plus prices on a regular schedule. Leave your email and we will send one short note if the best price drops 10% or more. No newsletter, no spam, unsubscribe by replying "stop".

Email me when it drops

One email per real price drop. Nothing else, ever.

Why the same box costs so much more at the vet

Vet clinics buy medications in small quantities and price them with a margin that helps keep the practice running. That is not a scam, but it does mean paying 2 to 3 times the online price for the identical product is common.

Large online pharmacies buy in volume and compete with each other in public, which pushes prices down. Promotions move prices around too: first-order coupons and autoship discounts can shift the effective price by 5 to 30 percent, so we list base prices and note promotions separately instead of mixing them together.

For prescription meds like Heartgard Plus, every accredited pharmacy performs the same step: it contacts your vet and verifies the prescription before shipping. The verification is identical everywhere, so a higher price does not buy better service.

Common questions

Is there a cheaper generic version of Heartgard Plus?

Yes. Ivermectin plus pyrantel generics such as Iverhart Max and Tri-Heart Plus contain the same active ingredient class and typically cost meaningfully less. Ask your vet whether a generic is right for your dog.

Why does my vet require a heartworm test before refilling?

Giving a preventative to a dog that already has heartworms can be dangerous, so most vets require a recent negative test before authorizing a new prescription. This is standard practice, not upselling.

Do online pharmacies handle the prescription?

Yes. You order, the pharmacy contacts your vet to verify the prescription, and it ships once approved. Having your clinic's name and phone number ready speeds it up.

General information only, not veterinary advice. Always consult your veterinarian about your pet's medications.

More in Heartworm & Intestinal Parasites